Coenzyme Q10 for fibromyalgia patients

Fibromyalgia is a serious complaint that affects women more frequently than men and occurs more frequently if there is a family history of the complaint. Fibromyalgia patients and chronic fatigue syndrome patients have similar symptoms: pain is perhaps the more common symptom for fibromyalgia patients while fatigue is often the predominant symptom in chronic fatigue syndrome. In both groups, there is a high probability of Coenzyme Q10 deficiency and a high probability that CoQ10 supplementation will alleviate symptoms.

Fibromyalgia is a chronic pain syndrome affecting an estimated 5% of people worldwide.  It is characterized by the following symptoms:

  • cognitive complaints related to concentration and memory
  • fatigue and a feeling of being tired much of the time
  • mood issues including anxiety and depression
  • muscle stiffness and soreness
  • sleep disorders

What it is that triggers fibromyalgia is not known with certainty and can vary from individual to individual.  Researchers hypothesize that fibromyalgia affects the ways in which the brain processes pain signals [Mayo Clinic].

Low Coenzyme Q10 associated with fibromyalgia

If we round up the usual suspects in our investigation of fibromyalgia, we end up making a connection between Coenzyme Q10 deficiency and fibromyalgia.

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Coenzyme Q10 and fibromyalgia

Fibromyalgia woman
Fibromyalgia patients have low Coenzyme Q10 levels and low serotonin levels.  Studies done in the Faculty of Medicine at the University of Sevilla, Spain, show that Coenzyme Q10 supplements can restore both Coenzyme Q10 and serotonin levels and can improve the symptoms of depression. Other studies show that Coenzyme Q10 supplementation can inhibit the inflammatory process and reduce oxidative stress damage.

Can we make a convincing argument for fibromyalgia patients to take a daily Coenzyme Q10 nutritional supplement?  If so, what is the basis for the argument?

Fibromyalgia is a complex disorder.  It causes pain, joint stiffness, debilitating fatigue, and difficulty thinking and remembering.  Its cause is not known; its treatment is uncertain.  It affects as many as five million Americans above the age of 18 years.  It affects many more women than men.

Coenzyme Q10 status and fibromyalgia
The first thing to know is that fibromyalgia is associated with low plasma Coenzyme Q10 levels [Garrido-Maraver 2014].

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