Pilot study news: A new study shows that Coenzyme Q10 supplementation reduces depression and fatigue in multiple sclerosis patients. This is good news indeed. Moreover, these are research results that make sense.
We know that Coenzyme Q10 supplementation improves the symptoms of both chronic fatigue syndrome patients [Castro-Marrero 2016] and fibromyalgia patients [Cordero 2013]. At least one study has shown that Coenzyme Q10 supplementation improves the symptoms of depression [Forester 2012].
Chronic, low-grade, systemic inflammation is common in many diseases: cardiovascular disease, metabolic syndrome, non-alcoholic fatty liver disease, obesity, type-2 diabetes [Zhai 2017]. Anti-inflammatory drugs give modest improvement at best and are associated with long-term adverse effects [Esser 2015]. Some researchers have begun to investigate whether Coenzyme Q10 as an adjunctive treatment has anti-inflammatory health benefits.
Energy starvation in the immune system? Immune system cells starved for energy? There is a very plausible theory that chronic heart failure is a disease caused by the energy starvation of the heart muscle cells. Lacking adequate Coenzyme Q10 – an indispensable component of the human cell respiration and oxidative phosphorylation process – the heart muscle cells produce less ATP than is needed to supply the cells with energy. (A concomitant theory holds that Coenzyme Q10, in its reduced form, also protects the heart muscle cells against oxidative damage.)