A meta-analysis of five randomized controlled clinical studies (n=449 infertile women) has shown that CoQ10 supplementation increases clinical pregnancy rates compared with placebo treatment or no treatment. The CoQ10 supplementation significantly increases clinical pregnancy rates both overall and in infertility subgroups such as the poor ovarian response subgroup (n=286) and the polycystic ovarian syndrome subgroup (n=163) [Florou 2020].
All study participants were women of reproductive age (mean age 33 years) diagnosed with either poor ovarian response or polycystic ovary syndrome. All were attending an assisted reproductive technology clinic [Florou 2020].
Coenzyme Q10 pre-treatment of young low-prognosis patients with diminished ovarian reserve or poor ovarian response increased the patients’ ovarian response to stimulation and improved oocyte and embryo quality.
After one completed assisted reproductive technique treatment cycle, the women treated with Coenzyme Q10 had a 32% pregnancy rate and a 29% live birth rate. The women in the control group had a pregnancy rate of 17% and a 16% live birth rate.
Coenzyme Q10 supplementation results in significantThe outcome of a clinical trial is thought to have statistical significance, or to be statistically significant, if the outcome is likely not caused by chance at a given statistical significance level, typically at the 0.05 level. Statistically significant outcomes may or may not be clinically significant. ... Read more about this term improvement in various sperm parameters: sperm density, sperm motility, and sperm morphology and, quite possibly, in pregnancy rates [Safarinejad].
Actually, we have known about the benefits of Coenzyme Q10 for treating men with significant abnormalities in sperm morphology and motility for 10 – 15 years now. Let’s have a look at the clinical research results reported in journal articles indexed by Medline.
CoQ10 and Male Infertility Associated with Abnormal Sperm Parameters
Safarinejad, M. R. (2009). Efficacy of Coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men. The Journal Of Urology, 182(1), 237–248.
Researchers enrolled 212 infertile men with various sperm abnormalities. Half of the patients were randomly assigned to receive 300 milligrams of Coenzyme Q10 daily, and half took matching placebos for 26 weeks. The researchers then continued to follow the patients’ progress for a 30-week treatment-free phase.
What about infertility problems and Coenzyme Q10, I was asked the other day. Mightn’t the improvement of cellular energy production and the protection against oxidative stress that Coenzyme Q10 supplements give, mightn’t they also help sperm quality and sperm motility? What about Coenzyme Q10 help for the quality of female egg cells?
Coenzyme Q10 and male infertility Nature Reviews: Urology In 2011, Dr. Annette Fenner, chief editor at Nature Reviews: Urology, published a note to the effect that supplementation with Coenzyme Q10 improves semen quality parameters and that the improvement in the sperm has been seen to be associated with improved pregnancy rates and live birth rates [Fenner].
Privacy & Cookies Policy
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.