Congestive heart failureThe Mayo Clinic defines heart failure, also known as congestive heart failure and/or chronic heart failure, as the failure of the heart muscle to pump blood to the body adequately. In other words, heart failure is not a heart attack, and it is not death from heart disease, which its name might seem to imply. Heart failure is a condition... Read more about this term. Chronic heart failureThe Mayo Clinic defines heart failure, also known as congestive heart failure and/or chronic heart failure, as the failure of the heart muscle to pump blood to the body adequately. In other words, heart failure is not a heart attack, and it is not death from heart disease, which its name might seem to imply. Heart failure is a condition... Read more about this term. The inability of the heart to pump adequate blood to the other body organs. In chronic heart failure, the left ventricular ejection fraction – the percentage of blood leaving the heart each time it contracts – is too low.
The medical term heart failure sounds like a death sentence. It does not mean sudden death, but the prognosis is usually not good. Heart failure is a disease that gets progressively worse.
The results of the Q-Symbio study give us good reason to think that CoQ10 adjunctive treatment, i.e. CoQ10 supplementation in addition to conventional medical treatment, can slow down the progression of the disease and improve the symptoms and the survival of heart failure patients [Mortensen].
Heart failure patients treated with daily Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term supplements in addition to their conventional heart failure medications have significantly lower death rates and significantly improved exercise capacity compared with heart failure patients treated with conventional medications alone [Lei].
This is the conclusion of the 2017 meta-analysis of relevant randomized controlled trialsRandomized controlled trials are studies in which patients or healthy volunteers are assigned at random (purely by chance) to receive one or more clinical interventions. One or more of the interventions is the active treatment being tested. Another of the interventions is the control against which the active treatment is being tested. The control is, typically, the standard practice or... Read more about this term reported by Li Lei and Yan Liu in the BMC Cardiovascular Disorders journal. The two cardiologists analyzed the results from 14 randomized controlled studies enrolling a total of 2149 patients.
Statin medications? What are we to think? StatinsStatins are a class of medications that effectively block the body’s synthesis of cholesterol. In so doing, statins also block the body’s synthesis of Coenzyme Q10.... Read more about this term undoubtedly lower cholesterol levels and reduce the number of heart attacks.
But statin medications can and do have adverse effects [Okuyama]. One of the undesirable unintended consequences of taking a statin medication is that the patient’s bio-synthesis of Coenzyme Q10 is also inhibited. The body produces cholesterol and Coenzyme Q10 in the same biological pathway. Cut off one, and you cut off the other as well.