Heart Failure and Coenzyme Q10 as Adjuvant Therapy

William Judy Cardiovascular Health May 15, 2022April 29, 2022ATP, coenzyme Q10, CoQ10, Ejection fraction, Free radicals, Heart, heart failure, Oxidative Stress, Q10 0 Comment

Heart failure – it sounds scary. It is scary, but the medical term heart failure does not mean that your heart stops beating. No, instead, it means that your heart can’t pump enough blood and oxygen to your body.

Dr. William Judy — In the 30-year study of the management of congestive heart failure patients, Dr. Judy found that CoQ10 therapy in addition to conventional medication is more effective than conventional medication alone; however, the patients’ response to the CoQ10 adjunctive treatment is fairly slow, with peak improvements coming within 8 – 12 months. The conventional medication plus CoQ10 therapy is safe; it improves long-term survival compared to conventional medication alone.

Heart failure may develop because the heart muscle has weakened or has become thicker and stiffer. Your heart muscle can compensate for a period, but, eventually, you will need treatment.

The thing to remember is that the heart tissue is muscle tissue. As such, it needs a constant supply of ATP energy, and Coenzyme Q10 is essential to the process of ATP energy generation [Crane 2001]. Furthermore, the heart muscle tissue needs protection against the oxidative damage caused by harmful free radicals, and Coenzyme Q10 in its reduced form is an important antioxidant [Crane 2001].

Combined Coenzyme Q10 and Selenium Supplementation

Richard Morrill Cardiovascular Health March 15, 2022April 22, 2022aging, Antioxidants, Cardiovascular, coenzyme Q10, CoQ10, elderly, Fibrosis, Heart, Inflammation, MicroRNA, Oxidative Stress, Q10, Selenium, Senior citizens, Supplementation, Supplements, Sweden 0 Comment

There is a special biological interrelationship between Coenzyme Q10 and selenium. From a cardiologist’s perspective, there is a theoretical advantage in using both substances to prevent heart disease if the patients’ intakes are sub-optimal [Alehagen & Aaseth 2015a].

Heart chambers — **Four years of daily supplementation of senior citizens with a combination of Coenzyme Q10 and selenium resulted in reduced risk of death from heart disease and in improved heart function.**

This advantage has been demonstrated in the outcomes of the KiSel-10 Study, a randomized controlled trial that enrolled elderly community dwelling Swedish citizens, average age 78 years, with known low serum selenium status (mean: 67.1 mcg/L) [Alehagen 2013; Alehagen 2016a; Alehagen 2016b].