Q10facts

Coenzyme Q10 Supplementation Increases ATP Levels

Richard Morrill Fibromyalgia January 15, 2022January 18, 2022ATP, coenzyme Q10, Energy, Fibromyalgia, Heart Health, Q10 0 Comment

Fact: Adequate Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More is essential for our cells’ generation of ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More energy.

Roger Federer — **For cells and tissues with high energy needs, tissues such as heart muscle tissue and skeletal muscle tissue, there is a constant demand for CoQ10 molecules.**

Adenosine triphosphateSee ATP More (ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More) molecules have been called the energy currency of the cells. ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More molecules have to be produced and stored for later use, similar to storing money in a bank. All of our cells contain ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More, and the ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More provides the energy for almost all cellular processes. ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More is, so to speak, what drives the cellular machinery.

CoQ10 molecules are vitamin-like substances that are an essential component of the oxidative phosphorylation process in the cells’ mitochondriaThe mitochondria are the bean-shaped organelles in the cells. They are the key organelles with responsibility for the production of ATP energy molecules. More; they are essential to the process that converts the energy from ingested carbohydrates and fatty acids into ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More [Schniertshauer 2016].

The Instability of Ubiquinol, Part 2 – Dog Studies

William Judy Ubiquinol December 30, 2021January 18, 2022Cmax, coenzyme Q10, heart failure, lipoprotein, Research, SIBR Research, Ubiquinol, ubiquinone 0 Comment

The results from large dog studies done by SIBR Research show that orally administered ubiquinol is mostly converted to the ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More by the time it reaches the small intestines [Judy 2021 Part 2].

Dr Judy in the lab — Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More is an essential bio-nutrient, especially important as we get older. It is a redox moleculeRedox is the abbreviated term for reduction-oxidation. Coenzyme Q10 molecules are redox molecules. Redox refers to the oxidation state of the molecule. Oxidized Coenzyme Q10 molecules, called ubiquinone (CoQ10), are Coenzyme Q10 molecules that can accept (take on) two electrons and thus become reduced Coenzyme Q10 molecules called ubiquinol. Reduced Coenzyme Q10 molecules, called ubiquinol (CoQH2), are Coenzyme Q10 molecules... More with an oxidized state called ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More and a reduced state called ubiquinol. Both are bio-active states. UbiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More supplements are more stable and much more tested than ubiquinol supplements. Ubiquinol by nature of being an electron donor is relatively quick to be oxidized to ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More.

In the small intestines, it is then absorbed primarily as ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More. Once it enters the lymph, it is increasingly converted back to ubiquinol.

By the time it leaves the lymph to enter the blood circulation, it is approximately 96 % ubiquinol again.

These findings beg the question: why buy a ubiquinol supplement when the ubiquinol will probably be converted to the ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More prior to absorption?

Coenzyme Q10 Supplementation for Elderly Persons

Richard Morrill Antiaging December 15, 2021January 18, 2022aging, coenzyme Q10, elderly, heart failure, Q10 0 Comment

Supplementation with Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More has primarily made use of the oxidized form called ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More. It is the stable form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More, the form with which all the important clinical studies have been done involving elderly persons, heart failureThe Mayo Clinic defines heart failure, also known as congestive heart failure and/or chronic heart failure, as the failure of the heart muscle to pump blood to the body adequately. In other words, heart failure is not a heart attack, and it is not death from heart disease, which its name might seem to imply. Heart failure is a condition... More patients, and Gulf War Illness patients [Alehagen 2013; Golomb 2014; Mortensen 2014].

Walk in autumn weather — When we reach the September of our years, our cells synthesize less and less of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More, the essential bio-nutrient that is needed for ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More energy generation, for antioxidantAntioxidants are substances that protect the cells and lipoproteins against the harmful effects of free radicals. They are substances that prevent the oxidation of other molecules and compounds. There are two broad categories of antioxidants: enzymatic and non-enzymatic. Non-enzymatic antioxidants are substances like Coenzyme Q10, vitamin C, vitamin E, glutathione, and various carotenoids. Prominent enzymatic antioxidants include catalase, glutathione peroxidase,... More defense against harmful free radicalsFree radicals are unstable and highly reactive molecules that are produced in the body during normal oxygen metabolism. Free radicals derived from oxygen are known as reactive oxygen species. Free radicals play both helpful and harmful roles in the body. Free radicals steal electrons from other substances in order to become stable. In so doing, the free radicals oxidize those... More, and for anti-inflammatory effects.

In study participants with low baseline seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More status, the combination of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More together with the essential trace element seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More appears to reduce the level of oxidative stress and inflammationInflammation is an immune system response to an injury to cells or tissues. It is the body’s attempt to defend against invaders such as bacteria andviruses and to mend the damage done by invaders. Typically, inflammation manifests itself in the form of fever and swelling, in the swarming of white blood cells and the release of cytokines to fight against... More and to delay or ameliorate the development of some age-related disorders [Aaseth 2021].

Coenzyme Q10 Supplementation for Fibromyalgia Patients

William Judy Fibromyalgia November 30, 2021January 18, 2022coenzyme Q10, Depression, Energy, Fatigue, Fibromyalgia, Pain, Q10 0 Comment

FibromyalgiaFibromyalgia is characterized by widespread muscle and bone pain. The pain is accompanied by fatigue, sleep, memory problems, and mood issues. Fibromyalgia seems to amplify the brain's processing of painful signals and sensations. Whereas the emphasis in chronic fatigue syndrome is on the persistent fatigue, the emphasis in fibromyalgia is on the widespread pain. Some studies have shown that CoQ10... More is a common chronic pain condition without a known cause and without a reliable, effective medical treatment. It has several signs and symptoms in common with chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... More: fatigue, pain, weakness, a feeling of discomfort in the body, a sense of unease and/or anxiety and depression.

Woman suffering from fibromyalgia — Treatment of fibromyalgiaFibromyalgia is characterized by widespread muscle and bone pain. The pain is accompanied by fatigue, sleep, memory problems, and mood issues. Fibromyalgia seems to amplify the brain's processing of painful signals and sensations. Whereas the emphasis in chronic fatigue syndrome is on the persistent fatigue, the emphasis in fibromyalgia is on the widespread pain. Some studies have shown that CoQ10... More generally involves physiotherapy, anti-convulsants, and antidepressant therapy. Adequate intake of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More, magnesium, seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More, vitamin D, and vitamin B12 may be beneficial.

Mitochondrial dysfunctionMitochondrial dysfunction is the loss of efficiency in the process of ATP energy production. As such, mitochondrial dysfunction is a factor in the ageing process and in virtually all chronic diseases including cancer, cardiovascular diseases, chronic fatigue syndrome and fibromyalgia, diabetes and metabolic syndrome, and neurodegenerative diseases. Coenzyme Q10 is an essential component in the mitochondrial production of ATP energy. More, oxidative stress, and inflammationInflammation is an immune system response to an injury to cells or tissues. It is the body’s attempt to defend against invaders such as bacteria andviruses and to mend the damage done by invaders. Typically, inflammation manifests itself in the form of fever and swelling, in the swarming of white blood cells and the release of cytokines to fight against... More have been associated with fibromyalgiaFibromyalgia is characterized by widespread muscle and bone pain. The pain is accompanied by fatigue, sleep, memory problems, and mood issues. Fibromyalgia seems to amplify the brain's processing of painful signals and sensations. Whereas the emphasis in chronic fatigue syndrome is on the persistent fatigue, the emphasis in fibromyalgia is on the widespread pain. Some studies have shown that CoQ10... More.

CoQ10 supplementation may restore an underlying deficit in CoQ10 status, which has been associated with fibromyalgiaFibromyalgia is characterized by widespread muscle and bone pain. The pain is accompanied by fatigue, sleep, memory problems, and mood issues. Fibromyalgia seems to amplify the brain's processing of painful signals and sensations. Whereas the emphasis in chronic fatigue syndrome is on the persistent fatigue, the emphasis in fibromyalgia is on the widespread pain. Some studies have shown that CoQ10... More, and may improve the fibromyalgiaFibromyalgia is characterized by widespread muscle and bone pain. The pain is accompanied by fatigue, sleep, memory problems, and mood issues. Fibromyalgia seems to amplify the brain's processing of painful signals and sensations. Whereas the emphasis in chronic fatigue syndrome is on the persistent fatigue, the emphasis in fibromyalgia is on the widespread pain. Some studies have shown that CoQ10... More patient’s outlook by:

The Instability of Ubiquinol Supplements – Lab Studies

William Judy Ubiquinol November 15, 2021January 18, 2022Absorption, coenzyme Q10, Instability, Q10, Stability, Ubiquinol, ubiquinone 0 Comment

At SIBR Research, we have long been concerned about misleading claims for ubiquinol supplements on the Web. It seems that there is a lack of understanding of the processes influencing the absorption and subsequent metabolism of ubiquinol. Moreover, this misunderstanding seems to have been exacerbated by some manufacturers’ incorrect claims regarding the bioavailability of their ubiquinol supplements [Mantle & Dybring 2020].

Dr William V Judy — SIBR Research studies show that the ubiquinol in supplements is very likely to be converted to ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More in the small intestines, to be absorbed as ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More, and then to be converted back to ubiquinol in the lymph.

Basic Information about Ubiquinone and Ubiquinol

Ubiquinol is the reduced form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More; it is the antioxidantAntioxidants are substances that protect the cells and lipoproteins against the harmful effects of free radicals. They are substances that prevent the oxidation of other molecules and compounds. There are two broad categories of antioxidants: enzymatic and non-enzymatic. Non-enzymatic antioxidants are substances like Coenzyme Q10, vitamin C, vitamin E, glutathione, and various carotenoids. Prominent enzymatic antioxidants include catalase, glutathione peroxidase,... More form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More.
UbiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More is the oxidized form of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More. It is essential for the process of ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More energy generation.

Note: Both forms of Coenzyme Q10 are bio-active forms.

Ubiquinone More Stable than Ubiquinol in Supplements

Ubiquinol molecules are electron donors. Thus, they are inherently unstable. They are constantly looking to give up two electrons. It is this property that first made us wonder whether the ubiquinol in supplements actually gets absorbed as ubiquinol or gets converted to ubiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials. More before being absorbed.

Low Coenzyme Q10 in Hereditary Hemochromatosis

Jan Aaseth Iron Overload October 30, 2021January 18, 2022 0 Comment

In a 2021 study, patients with hereditary hemochromatosis were observed to have significantly lower plasma concentrations of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More [Martinefski 2021].

Hereditary hemochromatosis is a genetic disorder that causes the body to build up too much iron in various organs including the heart and liver. The iron overload is toxic and can damage tissues and organs and lead to liver disease [CDC 2020].

The CDC reports that one-third of one percent of non-Hispanic Caucasians in the US has hereditary hemochromatosis. The rates are somewhat lower in other races and ethnic groups. It is more common for men to develop complications, often at an earlier age. Approximately one in ten men with hereditary hemochromatosis will develop severe liver disease.

Coenzyme Q10 for Traumatic Injury Patients in the Intensive Care Unit

Richard Morrill Intensive Care October 15, 2021January 18, 2022coenzyme Q10, ICU, Intensive Care, Q10, Trauma, Traumatic Injury 0 Comment

The administration of supplemental Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More in addition to conventional medical treatment has beneficial effects on traumatic injury patients in the intensive care unit and has no observed adverse effects.

Intubation — Prolonged mechanical ventilation of patients in intensive care units can have adverse effects. In this study, administration of 400 milligrams of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More daily significantly reduced the length of stay in the intensive care unit and the duration of the mechanical ventilation.

This is the conclusion from a clinical trialClinical trials are research studies in which various treatments, interventions, or tests are investigated for their safety and efficacy when used to detect, prevent, or treat diseases and medical conditions in patients and healthy volunteers. The gold standard for clinical trials are randomized, double-blind, placebo-controlled studies. More that enrolled patients who had been admitted to the intensive care unit [Hasanloei 2021].

The problem: trauma

-Traumatic injury is not uncommon: nearly one-third of the patients admitted to a typical intensive care unit in pre-Covid 19 days were admitted with traumatic injuries of one type or another.

Coenzyme Q10 and NADH in Chronic Fatigue Syndrome

William Judy Chronic fatigue syndrome September 30, 2021January 18, 2022CFS, Chronic Fatigue Syndrome, coenzyme Q10, Energy, NADH, Q10 0 Comment

Both Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More and NADH blood levels have been shown to be sub-optimal in patients diagnosed with chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... More [Castro-Marrero 2013; Maes 2009].

In chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... More, patients have the following symptoms:

fatigue that persists even after rest and sleep
generalized chronic pain
lack of motivation for physical and mental exertion
disruptions in concentration and memory
changes in sleep patterns and duration

Chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... More is a severe disabling condition without a good prognosis. There is no universally recognized treatment mode.

CoQ10 and NADH Combined Supplementation in Chronic Fatigue Syndrome

Now a randomized controlled trial published in 2021 shows that supplementation of chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... More patients with 200 mg of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More and 20 mg of NADH daily for 12 weeks has statistically significantThe outcome of a clinical trial is thought to have statistical significance, or to be statistically significant, if the outcome is likely not caused by chance at a given statistical significance level, typically at the 0.05 level. Statistically significant outcomes may or may not be clinically significant. More health benefits:

Coenzyme Q10 for Pets and Farm Animals and Race Horses

William Judy Exercise and Training September 15, 2021January 18, 2022Animals, coenzyme Q10, Dogs, Energy, Pets, Q10, Race Horses 0 Comment

Back in November of 2020, q10facts.com ran a story about the experimental use of CoQ10 supplementation in dogs, Cavalier King Charles Spaniels with mitral valve disease, to be precise. The study results showed that 2 times 100 mg daily had significantly raised the animals’ blood CoQ10 concentrations [Christiansen 2020]. Here we write about Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More for pets and farm animals and race horses.

Guest author Dr. William Judy, President of SIBR Research and Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More researcher for over 40 years. Here, lecturing at an International Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More Association conference in Bologna, Italy.

Coenzyme Q10 and Danny the Sheep

Just recently, I received an email about the CoQ10 experiences of a sheep farmer in the North of England who writes as follows:

Covid-19 and Coenzyme Q10 and Selenium

Richard Morrill Covid-19 August 30, 2021January 18, 2022coenzyme Q10, Corona virus, Covid-10, Q10, Selenium 0 Comment

In the UK, biochemist Iain R. Hargreaves and medical doctor David Mantle have written that the initial immune system response to the Covid-19 virus and the subsequent resolution of the resulting inflammationInflammation is an immune system response to an injury to cells or tissues. It is the body’s attempt to defend against invaders such as bacteria andviruses and to mend the damage done by invaders. Typically, inflammation manifests itself in the form of fever and swelling, in the swarming of white blood cells and the release of cytokines to fight against... More may well be dependent upon nutritional status, including micronutrient status. Accordingly, they have investigated the relationship between the status of two micronutrients, Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More and seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More, and the effect on oxidative stress and inflammationInflammation is an immune system response to an injury to cells or tissues. It is the body’s attempt to defend against invaders such as bacteria andviruses and to mend the damage done by invaders. Typically, inflammation manifests itself in the form of fever and swelling, in the swarming of white blood cells and the release of cytokines to fight against... More [Hargreaves & Mantle 2021].

Covid-19 test — In a 2021 review article, Hargreaves and Mantle write that adequate intakes of both Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More and seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More are necessary for optimal immune system defense against Covid-19 infections.

They conclude that optimal status of both Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More and seleniumSelenium (symbol Se, atomic number 34) is a trace element that is an essential nutrient and an essential component of some of the most important antioxidants in the body, in particular the selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Selenium is involved in the optimal functioning of the immune system. Professor Alehagen has pointed out that there exists a... More may be one aspect of an effective program to prevent and treat Covid-19 infections [Hargreaves & Mantle 2021]. The important thing in dealing with Covid-19 infections is to achieve and maintain a balance in the immune response against the virus without causing a cytokine storm as the cytokine storm is the cause of lung injury and respiratory distress in severe cases.

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