Combined Coenzyme Q10 and Selenium Supplementation

There is a special biological interrelationship between Coenzyme Q10 and selenium. From a cardiologist’s perspective, there is a theoretical advantage in using both substances to prevent heart disease if the patients’ intakes are sub-optimal [Alehagen & Aaseth 2015a].

Heart chambers
Four years of daily supplementation of senior citizens with a combination of Coenzyme Q10 and selenium resulted in reduced risk of death from heart disease and in improved heart function.

This advantage has been demonstrated in the outcomes of the KiSel-10 Study, a randomized controlled trial that enrolled elderly community dwelling Swedish citizens, average age 78 years, with known low serum selenium status (mean: 67.1 mcg/L) [Alehagen 2013; Alehagen 2016a; Alehagen 2016b].

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Covid-19 and Coenzyme Q10 and Selenium

In the UK, biochemist Iain R. Hargreaves and medical doctor David Mantle have written that the initial immune system response to the Covid-19 virus and the subsequent resolution of the resulting inflammation may well be dependent upon nutritional status, including micronutrient status. Accordingly, they have investigated the relationship between the status of two micronutrients, Coenzyme Q10 and selenium, and the effect on oxidative stress and inflammation [Hargreaves & Mantle 2021].

Covid-19 test
In a 2021 review article, Hargreaves and Mantle write that adequate intakes of both Coenzyme Q10 and selenium are necessary for optimal immune system defense against Covid-19 infections.

They conclude that optimal status of both Coenzyme Q10 and selenium may be one aspect of an effective program to prevent and treat Covid-19 infections [Hargreaves & Mantle 2021]. The important thing in dealing with Covid-19 infections is to achieve and maintain a balance in the immune response against the virus without causing a cytokine storm as the cytokine storm is the cause of lung injury and respiratory distress in severe cases.

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