CoQ10 Reduces Frequency and Duration of Migraine

Dr. Ross Pelton
Hello, my name is Ross Pelton. I am a pharmacist, nutritionist, author, and a health educator. My specialty is natural medicine and nutrition. I am also the world’s leading authority on the topic of drug-induced nutrient depletions. My website, bio and blog are available at: Here is a link for a FREE copy of my Quick Reference Guide to Drug-Induced Nutrient Depletions:

In April 2020, I published an article in Integrative Medicine: A Clinician’s Journal about the cardiovascular benefits of daily Coenzyme Q10 supplement [1]. As most of you know, Coenzyme Q10 is an important antioxidant, and it also plays critical roles in the mitochondrial production of energy in the form of ATP.

Endogenous production of Coenzyme Q10 peaks at about 20 years of age and then gradually declines throughout our adult years. One estimate is that the heart muscle cells of an 80-year-old will produce about half of the Coenzyme Q10 that the heart muscle cells of a 20-year-old will [2]. It is not practical to think about making up the difference by eating more or better. Consequently, daily CoQ10 supplementation is important [3].

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Coenzyme Q10 and migraine headaches

The migraine headache is characterized by severe throbbing pain, which is usually experienced on just one side of the head. Other symptoms include nausea, vomiting, and sensitivity to light and sound. Migraine attacks can last for many hours and even for days, and the pain can be so severe that it is disabling. Clinical studies have shown that daily Coenzyme Q10 supplements can help to reduce the frequency, the duration, and the intensity of migraine headaches.

Migraine headaches are more than just really bad tension-type headaches.  Migraine is a disabling neurological disease that keeps its victims from living and working normally.

Migraine is the third most prevalent disease in the world and the sixth most disabling disease in the world. Nearly one in four American households has a family member who suffers from migraine headaches [Migraine Research Foundation].

  • Migraine affects three times as many women as men. 
  • Migraine is most common between the ages of 25 and 55 years.
  • Migraine is a very expensive disease, both in terms of the expenditures for treatment and in terms of the lost production [Migraine Research Foundation]

Prophylactic treatment of migraine

Despite the prevalence and economic expense of migraine headaches, there are few medications approved to prevent its occurrence, and even fewer medications that do not have potentially serious adverse effects [Shoeibi].

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