In April 2020, I published an article in Integrative Medicine: A Clinician’s Journal about the cardiovascular benefits of daily Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both synthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More supplement [1]. As most of you know, Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both synthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More is an important antioxidantAntioxidants are substances that protect the cells and lipoproteins against the harmful effects of free radicals. They are substances that prevent the oxidation of other molecules and compounds. There are two broad categories of antioxidants: enzymatic and non-enzymatic. Non-enzymatic antioxidants are substances like Coenzyme Q10, vitamin C, vitamin E, glutathione, and various carotenoids. Prominent enzymatic antioxidants include catalase, glutathione peroxidase,... More, and it also plays critical roles in the mitochondrial production of energy in the form of ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production. More.

Endogenous production of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both synthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More peaks at about 20 years of age and then gradually declines throughout our adult years. One estimate is that the heart muscle cells of an 80-year-old will produce about half of the Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both synthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... More that the heart muscle cells of a 20-year-old will [2]. It is not practical to think about making up the difference by eating more or better. Consequently, daily CoQ10 supplementation is important [3].

MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More headaches are more than just really bad tension-type headaches.  MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More is a disabling neurological disease that keeps its victims from living and working normally.

MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More is the third most prevalent disease in the world and the sixth most disabling disease in the world. Nearly one in four American households has a family member who suffers from migraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More headaches [MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More Research Foundation].

• MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More affects three times as many women as men. 
• MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More is most common between the ages of 25 and 55 years.
• MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More is a very expensive disease, both in terms of the expenditures for treatment and in terms of the lost production [MigraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More Research Foundation]

Prophylactic treatment of migraine

Despite the prevalence and economic expense of migraineMigraine headaches are defined as unprovoked headaches that typically last from one to three days and are severe enough to limit or halt routine daily activity.  Typically, too, migraine headaches are accompanied by nausea and sensitivity to light and sound. Studies have shown that CoQ10 supplementation can help to prevent and treat migraine headache.  CoQ10 supplements have had statistically significant... More headaches, there are few medications approved to prevent its occurrence, and even fewer medications that do not have potentially serious adverse effects [Shoeibi].