Coenzyme Q10 and the Elderly

As we get older, staying active and maintaining our physical capacity is important if we are to avoid becoming frail and vulnerable to falls.

Elderly couple
In this article, we present information about the relationship of plasma Coenzyme Q10 status to the physical capacity and the frailty of elderly individuals.

Combining daily Coenzyme Q10 supplementation with daily physical activity is good therapy for avoiding sarcopenia, which is the clinical name for the loss of muscle mass caused by ageing.

Professor Guillermo Lopez-Lluch and his colleagues in Sevilla, Spain, have reported the following results from a cross-sectional study of 64 volunteers, 47 women and 17 men. Thirty-two of the volunteers in the study were between 65 and 75 years old, and 32 volunteers were 76 years or older [de la Bella-Garzón 2022].

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Coenzyme Q10 Supplementation Increases ATP Levels

Fact: Adequate Coenzyme Q10 is essential for our cells’ generation of ATP energy.

Roger Federer
For cells and tissues with high energy needs, tissues such as heart muscle tissue and skeletal muscle tissue, there is a constant demand for CoQ10 molecules.

Adenosine triphosphate (ATP) molecules have been called the energy currency of the cells. ATP molecules have to be produced and stored for later use, similar to storing money in a bank. All of our cells contain ATP, and the ATP provides the energy for almost all cellular processes. ATP is, so to speak, what drives the cellular machinery.

CoQ10 molecules are vitamin-like substances that are an essential component of the oxidative phosphorylation process in the cells’ mitochondria; they are essential to the process that converts the energy from ingested carbohydrates and fatty acids into ATP [Schniertshauer 2016].

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Coenzyme Q10 Supplementation for Fibromyalgia Patients

Fibromyalgia is a common chronic pain condition without a known cause and without a reliable, effective medical treatment. It has several signs and symptoms in common with chronic fatigue syndrome: fatigue, pain, weakness, a feeling of discomfort in the body, a sense of unease and/or anxiety and depression.

Woman suffering from fibromyalgia
Treatment of fibromyalgia generally involves physiotherapy, anti-convulsants, and antidepressant therapy. Adequate intake of Coenzyme Q10, magnesium, selenium, vitamin D, and vitamin B12 may be beneficial.

Mitochondrial dysfunction, oxidative stress, and inflammation have been associated with fibromyalgia.

CoQ10 supplementation may restore an underlying deficit in CoQ10 status, which has been associated with fibromyalgia, and may improve the fibromyalgia patient’s outlook by:

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Coenzyme Q10 and NADH in Chronic Fatigue Syndrome

Both Coenzyme Q10 and NADH blood levels have been shown to be sub-optimal in patients diagnosed with chronic fatigue syndrome [Castro-Marrero 2013; Maes 2009].

Dr. William V. Judy
Dr. Judy regards mitochondrial dysfunction, reduced immune function, and increased oxidative stress as biological explanations for the inverse association between CoQ10 and NADH status and the severity of chronic fatigue syndrome.

In chronic fatigue syndrome, patients have the following symptoms:

  • fatigue that persists even after rest and sleep
  • generalized chronic pain
  • lack of motivation for physical and mental exertion
  • disruptions in concentration and memory
  • changes in sleep patterns and duration

Chronic fatigue syndrome is a severe disabling condition without a good prognosis. There is no universally recognized treatment mode.

CoQ10 and NADH Combined Supplementation in Chronic Fatigue Syndrome

Now a randomized controlled trial published in 2021 shows that supplementation of chronic fatigue syndrome patients with 200 mg of Coenzyme Q10 and 20 mg of NADH daily for 12 weeks has statistically significant health benefits:

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Coenzyme Q10 for Pets and Farm Animals and Race Horses

Back in November of 2020, q10facts.com ran a story about the experimental use of CoQ10 supplementation in dogs, Cavalier King Charles Spaniels with mitral valve disease, to be precise. The study results showed that 2 times 100 mg daily had significantly raised the animals’ blood CoQ10 concentrations [Christiansen 2020]. Here we write about Coenzyme Q10 for pets and farm animals and race horses.

Dr. William Judy
Guest author Dr. William Judy, President of SIBR Research and Coenzyme Q10 researcher for over 40 years. Here, lecturing at an International Coenzyme Q10 Association conference in Bologna, Italy.

Coenzyme Q10 and Danny the Sheep

Just recently, I received an email about the CoQ10 experiences of a sheep farmer in the North of England who writes as follows:

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