End-of-the-year Coenzyme Q10 report card

Richard Morrill Cancer, Cardiovascular Health, Chronic fatigue syndrome January 2, 2018January 2, 2018 0 Comment

Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term as a nutritional supplement – if properly formulated – gets an A grade for performance. Coenzyme Q10 goes right to the head of the class on our list of daily nutritional supplements, right up there with vitamin D capsules, organic high-selenium yeast tablets, and fish oil capsules (if we don’t eat as much fish as we should).

As the fall semester 2017 drew to a close, I reviewed the published bio-medical documentation and assigned some performance grades to the nutritional supplement Coenzyme Q10. As might be expected of an “essential bio-nutrient,” Coenzyme Q10 maintained an exemplary grade point average.

Properly formulated Coenzyme Q10 supplements

Right. We want to get a supplement made with pharmaceutical-grade Coenzyme Q10 and manufactured under conditions of pharmaceutical control. We want a Coenzyme Q10 supplement that meets the following criteria:

Interview with Dr. Judy: the need for Coenzyme Q10

Richard Morrill Cardiovascular Health, Chronic fatigue syndrome, Statin Medications December 1, 2017December 1, 2017 0 Comment

Q. Good morning, Dr. Judy. You have talked with us about the safety of Coenzyme Q10 supplements, and you have told us that the formulation of the supplement is decisive for the absorption of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term. Shouldn’t we talk today about why we adults need daily Coenzyme Q10 supplements?

Coenzyme Q10 molecules are redox molecules. UbiquinoneUbiquinone, the oxidized form of Coenzyme Q10, expressed as Q10 or CoQ10, is absolutely essential for the mitochondrial ATP energy production process. Ubiquinone is the form of Coenzyme Q10 that the body synthesizes, and ubiquinone is the form of Coenzyme Q10 that has been extensively tested for safety, absorption, and efficacy in clinical trials.... Read more about this term can accept electrons, and ubiquinol can donate electrons. Oxireductase enzymes catalyze ubiquinone’s accepting electrons. Free radicalsFree radicals are unstable and highly reactive molecules that are produced in the body during normal oxygen metabolism. Free radicals derived from oxygen are known as reactive oxygen species. Free radicals play both helpful and harmful roles in the body. Free radicals steal electrons from other substances in order to become stable. In so doing, the free radicals oxidize those... Read more about this term take electrons from ubiquinol and become stable.

A. Yes, indeed. Coenzyme Q10 is very much needed and, at the same time, very little known by most people. Our bodies produce Coenzyme Q10 –called ubiquinone –, and Coenzyme Q10 is found in all of our cells except the red blood cells. That should tell us something.

Coenzyme Q10 and the energy starved heart

Richard Morrill Antiaging, Cardiovascular Health, Chronic fatigue syndrome June 22, 2017June 24, 2017 0 Comment

The number of bean-shaped mitochondriaThe mitochondria are the bean-shaped organelles in the cells. They are the key organelles with responsibility for the production of ATP energy molecules.... Read more about this term in our cells varies according to the energy needs of the various organs. The cells in organs with high energy needs, e.g. the heart, the liver, the skeletal muscle, will have greater numbers of mitochondria than will the cells of less active organs, e.g. the skin. Adequate supply of Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term is necessary to keep the mitochondria actively producing ATPATP (adenosine triphosphate) molecules are the high-energy molecules with easily broken phosphate bonds that release energy to the energy-requiring processes in the cells. Coenzyme Q10 is essential to the process of ATP production.... Read more about this term molecules.

Cellular respiration is the name for the process by which the ATP molecules are produced inside the mitochondria in our cells. Coenzyme Q10 in its oxidized form is an essential component in this process of energy production.

Fewer Coenzyme Q10 molecules in the mitochondria inevitably mean less ATP energy production. Fewer ATP molecules mean less energy for our cells.

Heart muscle cells with low Coenzyme Q10 concentrations and with fewer ATP molecules produced make for an energy starved heart.

Coenzyme Q10 improves chronic fatigue syndrome symptoms

Richard Morrill Chronic fatigue syndrome June 17, 2017June 22, 2017 1 Comment

Tired woman at computer — Fatigue. Loss of memory and concentration. Sleep that does not refresh you. Feeling of exhaustion lasting 24 hours or more. These are symptoms of chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... Read more about this term. Supplementation with a well-documented Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term supplement can help.

Some very interesting studies of the treatment of chronic fatigue syndrome patients with oral Coenzyme Q10 supplements have revealed improved symptoms for as long as the treatment continued. What happened in these studies?

The chronic fatigue syndrome patients in these studies had abnormally low plasma and tissue (leg muscle) Coenzyme Q10 concentrations at baseline. Oral administration of a well-formulated Coenzyme Q10 dissolved in vegetable oil resulted in significantThe outcome of a clinical trial is thought to have statistical significance, or to be statistically significant, if the outcome is likely not caused by chance at a given statistical significance level, typically at the 0.05 level. Statistically significant outcomes may or may not be clinically significant. ... Read more about this term increases in plasma and tissue Coenzyme Q10 levels.

Coenzyme Q10 and chronic fatigue syndrome

Richard Morrill Chronic fatigue syndrome April 10, 2017June 23, 2017 2 Comments

Tired woman — Patients diagnosed with chronic fatigue syndromeChronic fatigue syndrome (CFS) is a complicated disorder with an unknown cause. CFS is characterized by persistent fatigue that does not improve with rest and that cannot be explained by any identifiable medical condition. CFS is also known as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID). It is sometimes abbreviated ME/CFS. CFS patients typically have low levels of... Read more about this term have abnormally low plasma (and muscle tissue) Coenzyme Q10Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term concentrations. Supplementation with a well-formulated Coenzyme Q10 preparation improves symptoms.

Chronic fatigue syndrome is a complicated illness. As its name states, it is a chronic condition, and it is characterized by a debilitating fatigue. The fatigue may be exacerbated by physical or mental exertion. Strangely enough, the fatigue is not alleviated by rest or relaxation [Mayo Clinic].

The cause of chronic fatigue syndrome is still unknown. The major symptom, the chronic fatigue, is also seen in such related conditions as myalgic encephalomyelitis (ME) and systemic exertion intolerance disease (SEID) [Mayo Clinic].