As we get older – and more susceptible to aging-related diseases – the The mitochondria are the bean-shaped organelles in the cells. They are the key organelles with responsibility for the production of ATP energy molecules.... Read more about this term and the endoplasmic reticula in our cells synthesize significantly less Coenzyme Q10 molecules are fat-soluble molecules that are both bsynthesized in the body and ingested in the diet and in supplements. Coenzyme Q10 is synthesized in the body in the same biological pathway as cholesterol. Bio-synthesis of Coenzyme Q10 begins to decline once humans reach their adult years. The reduced production of Coenzyme Q10 cannot be compensated in any practical... Read more about this term. This seems to be especially true of CoQ10 bio-synthesis in the heart muscle cells, kidney cells, leg muscle cells, and abdominal wall muscle cells [Díaz-Casado 2019].
In some human tissues, the highest levels of CoQ10 are found in 20-year-olds. After the 20’s comes the ageing-related decline in CoQ10 levels in various human tissues [Kalén 1989].