Dr. Crane (1925-2016) is credited with the discovery and isolation of Coenzyme Q10 from beef heart mitochondria in 1957.
Dr. Crane sent samples of the new substance to Dr. Karl Folkers at the Merck Research Labs, and Dr. Folkers determined the chemical structure of the substance in 1958. At the end of his life, Dr. Crane was searching for evidence for a role for Coenzyme Q10 in the treatment of autism.C-reactive protein (CRP): C-reactive protein is a protein produced in the liver in response to inflammation. High levels of C-reactive protein in the blood are bio-markers for inflammation. Clinical studies have shown that Coenzyme Q10 supplementation is associated with reduced levels of C-reactive protein and thus with reduced levels of inflammation.